Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition?
نویسندگان
چکیده
منابع مشابه
Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells
BACKGROUND Disturbances in lipid homeostasis and myelination have been proposed in the pathophysiology of schizophrenia and bipolar disorder. We have previously shown that several antipsychotic and antidepressant drugs increase lipid biosynthesis through activation of the Sterol Regulatory Element-Binding Protein (SREBP) transcription factors, which control the expression of numerous genes invo...
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عنوان ژورنال:
- Journal of lipid research
دوره 54 2 شماره
صفحات -
تاریخ انتشار 2013